A diagnostic model for minimal change disease based on biological parameters

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چکیده

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A diagnostic model for minimal change disease based on biological parameters

Background Minimal change disease (MCD) is a kind of nephrotic syndrome (NS). In this study, we aimed to establish a mathematical diagnostic model based on biological parameters to classify MCD. Methods A total of 798 NS patients were divided into MCD group and control group. The comparison of biological indicators between two groups were performed with t-tests. Logistic regression was used t...

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Minimal change disease (MCD) is a histopathological lesion in the kidney that is most commonly associated with nephrotic syndrome. The majority of the cases are idiopathic. Pathogenesis is not well understood, although T-cell-related mechanisms are implicated. Massive proteinuria leads to hypoalbuminemia, salt retention, disorder of hemostasis, hyperlipidemia and increased susceptibility to inf...

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ژورنال

عنوان ژورنال: PeerJ

سال: 2018

ISSN: 2167-8359

DOI: 10.7717/peerj.4237